Looking for High Purity Chlorhexidine Base Supplier in India?
Chlorhexidine has been trusted in antiseptic and antimicrobial formulations for over seventy years now, and at the center of that entire product family sits one compound — Chlorhexidine Base. It's not usually the finished product itself, but rather the starting point from which the more familiar chlorhexidine salts and solutions get built. Get the base right, and everything downstream tends to follow.
Because of its chemical structure, Chlorhexidine Base acts as the core intermediate for synthesizing high-demand derivatives such as Chlorhexidine Gluconate, Hydrochloride, and Acetate. Formulators relying on these active antiseptics need a base compound that meets strict purity benchmarks, ensuring predictable stoichiometry and reaction yields during downstream salt formation.
At Alex Pharmachem, we manufacture Chlorhexidine Base at our dedicated facility in Ankleshwar with a 600 MT annual capacity. Whether used for captive production of our own derivative lines or supplied directly to international formulation partners, every batch is supported by complete WHO-GMP documentation and Drug Master Files (DMFs).
Annual Production Capacity
600 MT / Year — Dedicated manufacturing plant supplying export, domestic sales, and captive synthesis.
General Information
Chlorhexidine Base is an active substance which possesses the Chemical Abstracts Service Registry Number of 55-56-1 with its chemical structure represented by the formula C22H30Cl2N10 and its molecular weight being equal to 505.45g/mole. Chlorhexidine Base belongs to the category of biguanides which is defined by a high level of antimicrobial activity of such substances. The use of this substance started in the year 1953 in the United Kingdom where it was marketed as "Hibitane".Since then, it has grown into one of the most trusted antiseptics used in both human and veterinary practice due to its high efficiency against both Gram-positive and Gram-negative bacteria.
Chlorhexidine Base is manufactured by us as an intermediate, manufactured in a specific facility with a production capacity of 600 MT per year for export purposes, domestic sales, and also captive consumption, which means that it is used for manufacturing our higher end chlorhexidine products such as Chlorhexidine Gluconate 20% Solution, Chlorhexidine HCl, and Chlorhexidine Acetate. The captive consumption factor mentioned above is significant for a variety of reasons. In case the base chemical and its salts are manufactured within a company’s premises, the possibility of maintaining consistency within the chlorhexidine product line is much greater.
Our facility operates under WHO-GMP, FDA, Written Confirmation (WC), ISO, and HALAL certifications, and we maintain Drug Master Files (DMFs) across our product range — chlorhexidine included. That regulatory backbone is part of why formulators sourcing chlorhexidine derivatives from us aren't just buying a chemical; they're buying into a documented, traceable supply chain.
As a base compound, Chlorhexidine Base itself has low solubility in water, which is precisely why it's typically converted into water-soluble salt forms — gluconate, acetate, hydrochloride — for most practical antiseptic and disinfectant applications. The base form remains essential, though, as the true starting material every one of those salts derives from.
Applications
Chlorhexidine Base serves primary synthetic and derivative formulation roles:
Manufacturing intermediate for Chlorhexidine salts
Its primary use is as the manufacturing intermediate for chlorhexidine salts, which are then used in making Chlorhexidine Gluconate 20% Solution, Chlorhexidine HCl, and Chlorhexidine Acetate.
Broad-spectrum antiseptic & disinfectant formulation
In turn, the chlorhexidine salts find numerous applications in various antiseptics and disinfectants - skin disinfectants, wound management agents, oral care products, and surface disinfectants in medical and veterinary practice.
Surgical scrub & pre-operative preparation
Chlorhexidine products are also widely employed in scrubbing preparations for surgery and before surgery skin preparation where there is an urgent need for effective and broad-spectrum antibacterial activity.
